Milvexian and other drugs targeting Factor XI: a new era of anticoagulation?


Published: 15 April 2022
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Authors

  • Marco P. Donadini Research Center on Thromboembolic Diseases and Antithrombotic Therapies, Department of Medicine and Surgery, University of Insubria, Varese; Thrombosis and Hemostasis Center, Ospedale di Circolo e Fondazione Macchi, Azienda Socio-Sanitaria territoriale dei Sette Laghi, Varese, Italy.
  • Walter Ageno Research Center on Thromboembolic Diseases and Antithrombotic Therapies, Department of Medicine and Surgery, University of Insubria, Varese; Thrombosis and Hemostasis Center, Ospedale di Circolo e Fondazione Macchi, Azienda Socio-Sanitaria territoriale dei Sette Laghi, Varese, Italy.

For almost 90 years, the discovery and development of anticoagulant drugs have focused on maximizing their antithrombotic efficacy while minimizing the risk of bleeding, in addition to providing manageable compounds with predictable and/or monitorable effects [...].


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Donadini, M. P., & Ageno, W. (2022). Milvexian and other drugs targeting Factor XI: a new era of anticoagulation?. Bleeding, Thrombosis, and Vascular Biology, 1(1). https://doi.org/10.4081/btvb.2022.22

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