Is non-alcoholic fatty liver disease a prothrombotic risk factor?
Published: May 19 2023
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
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Citations
Ajmera V, Cepin S, Tesfai K, et al. A prospective study on the prevalence of NAFLD, advanced fibrosis, cirrhosis and hepatocellular carcinoma in people with type 2 diabetes. J Hepatol. 2022; Available from: https://www.sciencedirect.com/science/article/pii/S0168827822033025 DOI: https://doi.org/10.1016/j.jhep.2022.11.010
Anstee QM, Targher G, Day CP. Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis. Nat Rev Gastroenterol Amp Hepatol. 2013; 10:330–45. DOI: https://doi.org/10.1038/nrgastro.2013.41
Stine JG, Argo CK, Pelletier SJ, et al. Advanced non-alcoholic steatohepatitis cirrhosis: A high-risk population for pre-liver transplant portal vein thrombosis. World J Hepatol. 2017; 9:139–46. DOI: https://doi.org/10.4254/wjh.v9.i3.139
Tripodi A, Fracanzani AL, Primignani M, et al. Procoagulant imbalance in patients with non-alcoholic fatty liver disease. J Hepatol. 2014; 61:148–54. DOI: https://doi.org/10.1016/j.jhep.2014.03.013
Tripodi A. Detection of procoagulant imbalance. Modified endogenous thrombin potential with results expressed as ratio of values with-to-without thrombomodulin. Thromb Haemost. 2017; 117:830–6. DOI: https://doi.org/10.1160/TH16-10-0806
Potze W, Siddiqui MS, Boyett SL, Adelmeijer J, et al. Preserved hemostatic status in patients with non-alcoholic fatty liver disease. J Hepatol. 2016; 65: 980–7. DOI: https://doi.org/10.1016/j.jhep.2016.06.001
Cerletti C, Colucci M, Storto M, Semeraro F, et al. Randomised trial of chronic supplementation with a nutraceutical mixture in subjects with non-alcoholic fatty liver disease. Br J Nutr. 2020; 123:190–7. DOI: https://doi.org/10.1017/S0007114519002484
Valenti L, Tripodi A, La Mura V, et al. Clinical and genetic determinants of the fatty liver-coagulation balance interplay in individuals with metabolic dysfunction. JHEP Rep. 2022; 4:100598. DOI: https://doi.org/10.1016/j.jhepr.2022.100598
Paolini E, Longo M, Corsini A, Dongiovanni P. The Non-Invasive Assessment of Circulating D-Loop and mt-ccf Levels Opens an Intriguing Spyhole into Novel Approaches for the Tricky Diagnosis of NASH. Int J Mol Sci. 2023; 24:23-31. DOI: https://doi.org/10.3390/ijms24032331
Pasarín M, La Mura V, Gracia-Sancho J, et al. Sinusoidal endothelial dysfunction precedes inflammation and fibrosis in a model of NAFLD. PloS One. 2012; 7:e32785. DOI: https://doi.org/10.1371/journal.pone.0032785
Tripodi A, Lombardi R, Primignani M, et al. Hypercoagulability in Patients with Non-Alcoholic Fatty Liver Disease (NAFLD): Causes and Consequences. Biomedicines. 2022; 10:249. DOI: https://doi.org/10.3390/biomedicines10020249
Kopec AK, Joshi N, Towery KL, et al. Thrombin inhibition with dabigatran protects against high-fat diet-induced fatty liver disease in mice. J Pharmacol Exp Ther. 2014; 351:288–97. DOI: https://doi.org/10.1124/jpet.114.218545
How to Cite
Is non-alcoholic fatty liver disease a prothrombotic risk factor?. (2023). Bleeding, Thrombosis and Vascular Biology, 2(2). https://doi.org/10.4081/btvb.2023.81
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