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  Diagnostic and management practices for inherited fibrinogen disorders: a nationwide survey of Italian Hemophilia Treatment Centers

  Renato Marino, Silvia Linari, Marzia Leotta, Antonio Coppola, Chiara Biasoli, Maria Elisa Mancuso, Flora Peyvandi, Cristina Santoro, Ezio Zanon, Rita Carlotta Santoro

  02-12-2025

  https://doi.org/10.4081/btvb.2025.372

  938

  PDF: 122

  HTML: 130

  Supplementary: 79

  Appendix: 80

• PO073 | ANALYTICAL VARIABILITY IN FIBRINOGEN TESTING REVEALING FIBRINOGEN LONGMONT: A CASE REPORT A. Paradiso¹, S. Cmet², E. Fontanini² | ¹Dep. of Medicine, University of Udine, Udine, Italy; ²Dep. of Laboratory Medicine, Institute of Clinical Pathology, Azienda Ospedaliera Universitaria Friuli Centrale, Udine, Italy

  Antonella Paradiso

  26-10-2026

  https://doi.org/10.4081/btvb.2026.889

  36

  PDF: 22
• 

  The key to fibrinolysis and thrombolysis

  Roger Lijnen, Désiré Collen

  09-09-2025

  https://doi.org/10.4081/btvb.2025.368

  1707

  PDF: 531

  HTML: 264

• PO66 | Viscoelastic tests in disseminated intravascular coagulation associated with aortic aneurysm A. M. Pizzini¹, C. Biasoli², M. Bovara³, E. Gesuete¹, A. Fusco¹, C. Fantoni¹, P. Pedrazzi², R. Mancini³, M. Silingardi¹ | ¹Ambulatorio Emostasi & Trombosi, Dipartimento Medico, Ospedale Maggiore AUSL Bologna; ²SSI Presa in Carico delle Malattie Emorragiche e Tromboemboliche della Romagna; ³Laboratorio Unico Metropolitano AUSL Bologna, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.335

  662

  PDF: 21
• 

  Plasma fibrinogen levels and all-cause and cause-specific mortality in an Italian adult population: results from the Moli-sani study

  Roberta Parisi, Simona Costanzo, Romy de Laat-Kremers, Augusto Di Castelnuovo, Amalia De Curtis, Teresa Panzera, Mariarosaria Persichillo, Chiara Cerletti, Giovanni de Gaetano, Maria Benedetta Donati, Licia Iacoviello, Bas de Laat , for the Moli-sani Study Investigators

  27-01-2023

  https://doi.org/10.4081/btvb.2023.46

  2411

  PDF: 858

  APPENDIX: 229

• CO-66 | PREGNANCY OUTCOMES AND PERIPARTUM MANAGEMENT IN WOMEN WITH CONGENITAL FIBRINOGEN DISORDERS: A SINGLE-CENTRE EXPERIENCE T. Martini¹, B. Borsellino^1|2, B. Pollio¹ | ¹Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Torino, Italy; ²Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Rome Tor Vergata, Roma, Italy

  Tiziano Martini

  14-10-2026

  https://doi.org/10.4081/btvb.2026.676

  66

  PDF: 20
• 

  Circulating albumin-to-fibrinogen ratio may be a risk indicator for venous thromboembolism: findings from a population-based prospective cohort study

  Setor K. Kunutsor, Sudhir Kurl, Ari Voutilainen, Jari Laukkanen

  14-07-2022

  https://doi.org/10.4081/btvb.2022.36

  1702

  PDF: 404
• 

  Addressing some challenges of congenital fibrinogen disorders in 2023 and beyond

  Cristina Santoro, Alessandro Casini

  03-08-2023

  https://doi.org/10.4081/btvb.2023.75

  1741

  PDF: 608

• CO40 | The co-inheritance of two ITGB3 variants exerting additive detrimental effects on platelets leads to variant Glanzmann thrombasthenia N. Arndt¹, E. Falcinelli¹, A. Zamora-Cánovas², A. Sánchez Fuentes², A. Marín-Quilez², I. Tano¹, M.D.M. Nieto-Hernández³, J.M. Bastida⁴, J. Rivera², P. Gresele¹, L. Bury¹ | ¹Department of Medicine and Surgery, Section of Internal and Cardiovascular Medicine, University of Perugia, Italy; ²Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla, ISCIII-CIBERER, Murcia, Spain; ³Servicio de Hematología, Hospital Universitario de Jaen, Spain; ⁴Departamento de Hematología, Complejo Asistencial Universitario de Salamanca “CAUSA”, Instituto de Investigación Biomédica de Salamanca “IBSAL”, Centro de Investigación del Cáncer, IBMCC-CSIC, Universidad de Salamanca “USAL”, Salamanca, Spain

  22-10-2025

  https://doi.org/10.4081/btvb.2025.247

  631

  PDF: 21
• 

  PO42 | DIFFERENTIAL EXPRESSION OF HEMOSTATIC BIOMARKERS ACROSS CANCER TYPE AND DISEASE STAGE: A PROSPECTIVE ANALYSIS OF 4,292 PATIENTS FROM THE HYPERCAN STUDY P. Gómez-Rosas^1|2|, D. Romeo¹, S. Bolognini¹, C. Ticozzi¹, F. Schieppati¹, A. D’Alessio⁴, R. Labianca⁴, A. Falanga^1|5|6, M. Marchetti^1|5|6 | ¹Hospital Papa Giovanni XXIII, Bergamo, Italy; ²Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands; ³Hospital de Oncologia, Unidad Medica de Alta Especialidad (UMAE), Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Mexico City, Mexico; ⁴Fondazione ARTET Onlus, Bergamo, Italy; ⁵ERN EuroBloodNet; ⁶School of Medicine and Surgery, University of Milan Bicocca, Italy; *On Behalf Of The Hypercan Investigators

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.536

  518

  PDF: 115
• 

  The landscape of rare coagulation factor deficiency management in Italy: a national hemophilia center survey

  Silvia Linari, Renato Marino, Marzia Leotta, Antonio Coppola, Patrizia Di Gregorio, Augusto Bramante Federici, Flora Peyvandi, Cristina Santoro, Ezio Zanon, Rita Carlotta Santoro

  05-11-2025

  https://doi.org/10.4081/btvb.2025.369

  1368

  PDF: 221

  HTML: 137

  Appendix: 121

• CO066 | COAGULOPATHY IN CAR-T CELL-TREATED PATIENTS WITH LYMPHOPROLIFERATIVE DISORDERS: A RETROSPECTIVE, SINGLE-CENTER OBSERVATIONAL STUDY I. Santo¹, R. Morganti², G. Leoni³, G. Tancredi³, L. Contino⁴, S. Galimberti³, R.M. Santi⁴, E. Orciuolo⁵ | ¹Azienda Toscana Nord Ovest, Versilia Hospital, Italy; ²Hematology Division AOUP, Pisa, Italy; ³University of Pisa, Hematology Pisa, Italy; ⁴Azienda Ospedaliera Universitaria Alessandria, Italy; ⁵Azienda Ospedaliera Universitaria Pisana, Hematology Pisa, Italy

  Ignazio Santo

  26-10-2026

  https://doi.org/10.4081/btvb.2026.768

  58

  PDF: 25

• CO-67 | CONGENITAL DYSFIBRINOGENEMIA: BLEEDING PHENOTYPE, THROMBOTIC COMPLICATIONS, AND LONG-TERM MANAGEMENT IN A MULTICENTER COHORT M. Biglietto^1|2, M. Presti¹, R.C. Santoro³, I. Nichele⁴, M. Napolitano⁵, S. Pasca⁶, A. Borchiellini⁷, B. Pollio⁸, E. Zanon⁹, G. Barillari¹⁰, A. Poz¹⁰, S. Sorella¹, S. Ligia¹, R. Mormile¹, E. Baldacci¹, G. Castaman¹¹, F. Peyvandi^12|13, C. Santoro¹ | ¹Hematology, Department of Translational and Precision Medicine, Sapienza University of Rome, Italy; ²Department of Molecular Biology, Sapienza University of Rome, Italy; ³Hemostasis and Thrombosis Unit, Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy; ⁴Hematology Unit, Azienda ULSS 8 Berica - San Bortolo Hospital, Vicenza, Italy; ⁵Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Italy; ⁶Coagulation Diseases Center, Transfusion Medicine Department - Azienda Sanitaria Universitaria Integrata del Trentino, Trento, Italy; ⁷Centro di Riferimento Regionale Malattie Emorragiche e Trombotiche dell'Adulto, Divisione di Ematologia, Università Città della Salute e della Scienza di Torino, Italy; ⁸SIMT Immunohematology and Transfusion Medicine Service, Diagnostic Department, A.O. Città della Salute e della Scienza, Torino, Italy; ⁹Department of Medicine, Haemophilia Centre, University Hospital of Padua, Italy; ¹⁰Center for Hemorrhagic and Thrombotic Diseases, General and University Hospital S. Maria della Misericordia, Udine, Italy; ¹¹Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze, Italy; ¹²IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milano, Italy; ¹³Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milano, Italy

  Mario Biglietto

  14-10-2026

  https://doi.org/10.4081/btvb.2026.677

  57

  PDF: 18

• CO010 | MAPPING HEMOSTATIC BIOMARKER EXPRESSION ACROSS CANCER TYPES AND STAGES WITHIN THE HYPERCAN COHORT P. Gómez-Rosas^1|2, D. Romeo¹, S. Bolognini¹, C. Ticozzi¹, F. Schieppati^1|4|5, A. D’Alessio³, R. Labianca³, L. Barcella^1|4|5, A. Falanga^3|5, M. Marchetti^1|4|5 | ¹Hospital Papa Giovanni XXIII, Bergamo, Italy; ²Hospital de Oncología, Unidad Médica de Alta Especialidad (UMAE), Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Ciudad de México, México; ³Fondazione ARTET Onlus, Bergamo, Italy; ⁴ERN EuroBloodNet; ⁵School of Medicine and Surgery, University of Milan Bicocca, Italy. On behalf of the HYPERCAN Investigators

  Marina Marchetti

  26-10-2026

  https://doi.org/10.4081/btvb.2026.712

  135

  PDF: 23

• PO101 | COMPREHENSIVE EVALUATION OF COAGULATION PROFILES IN REFRACTORY MODERATE-TO-SEVERE ULCERATIVE COLITIS L. Spiezia¹, G. Di Lecce², B. Barberio², M. Zanconato², E. Bicego¹, C. Samà¹, B. Serena¹, M. De Bona³, A. Buda³, F. Zingone², E.V. Savarino², P. Simioni¹ | ¹First Chair of Internal Medicine, Department of Medicine (DIMED), Padova University Hospital, Padova, Italy; ²Gastroenterology Unit, Department of Surgery, Oncology and Gastroenterology (DISCOG), University of Padova, Padova, Italy; ³Gastroenterology Unit, Department of Oncological Gastrointestinal Surgery, S. Maria del Prato Hospital, Feltre, Italy

  Luca Spiezia

  26-10-2026

  https://doi.org/10.4081/btvb.2026.917

  43

  PDF: 23

• CO37 | Assessment of clotting factor activity and sterility in thawed fresh frozen plasma supplied to helicopter emergency medical services for prehospital transfusion D. Romeo¹, M. Marchetti^1,2, M. Testa¹, A. Motta¹, P. Gomez-Rosas¹, G. Ravasio¹, F. Daminelli³, L. Barcella¹, A. Falanga^1,2 | ¹Immunohematology and Transfusion Medicine Department, Hospital Papa Giovanni XXIII, Bergamo; ²School of Medicine and Surgery, University Milano Bicocca, Milan; ³Anesthesia and Resuscitation Department, Hospital Papa Giovanni XXIII, Bergamo, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.244

  691

  PDF: 22

• PO91 | Disseminated intravascular coagulation with deep vein thrombosis in a frail patient: an extreme manifestation triggered by sepsis during SGLT2i therapy M. Vacca¹, M.V. Cherchi¹, S. Che¹, G.A.M.L. Costanzo², D. Firinu², M. Mantega¹, S. Del Giacco² | ¹Ospedale Sirai, ASL Sulcis, ²Università degli Studi di Cagliari, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.361

  810

  PDF: 22
• 

  PO44 | PREDICTORS OF ONE-YEAR MORTALITY IN NEWLY DIAGNOSED METASTATIC BREAST CANCER: THE PROGNOSTIC ROLE OF HEMOSTATIC BIOMARKERS AND EARLY THROMBOEMBOLISM M. Marchetti^1|2|3, P. Gomez-Rosas^1|4|5, S. Bolognini¹, C. Ticozzi¹, D. Romeo¹, F. Schieppati^1|3, L. Barcella^1|3, F. Petrelli⁶, A. D'Alessio⁷, R. Labianca⁷, A. Falanga^1|2|3 | ¹Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; ²School of Medicine and Surgery, University of Milan Bicocca, Milan, Italy; ³ERN EuroBloodNet; ⁴Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands; ⁵Hospital de Oncologia, Unidad Medica de Alta Especialidad (UMAE), Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Mexico City, Mexico; ⁶Oncology Unit, Hospital Treviglio-Caravaggio, Treviglio, Italy; ⁷Fondazione ARTET Onlus, Bergamo, Italy; *On behalf of the Hypercan Investigators

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.538

  484

  PDF: 109

• PO052 | VALIDATION OF THROMBIN GENERATION MEASUREMENT IN PLATELET- RICH-PLASMA: EVOLUTION IN THE ST GENESIA^® SYSTEM F. Bocchi^1|2, R. Pastorino^1|2, G. Murante^1|2|3, S. Bergonzi^1|2|3, M. Capetta^1|2|3, F. Valeri^2|3, C. Dainese^2|3, A. Valpreda⁴, B. Bruno^1|3, A. Borchiellini^2|3 | ¹Department of Molecular Biotechnology and Health Sciences, University of Turin, Torino, Italy; ²Regional Centre for Thrombotic and Hemorrhagic Diseases, AOU Città della salute e della Scienza di Torino, Torino, Italy; ³Division of Hematology, AOU Città della Salute e della Scienza, Università di Torino, Torino, Italy; ⁴Central Lab Baldi and Riberi, AOU Città della salute e della Scienza di Torino, Torino, Italy

  Francesca Bocchi

  26-10-2026

  https://doi.org/10.4081/btvb.2026.868

  40

  PDF: 27

• CO-70 | CONGENITAL AFIBRINOGENEMIA: BLEEDING PHENOTYPE, THROMBOTIC COMPLICATIONS, AND LONG-TERM MANAGEMENT IN A MULTICENTER COHORT M. Biglietto^1|2, M. Presti¹, R.C. Santoro³, I. Nichele⁴, M. Napolitano⁵, S. Pasca⁶, A. Borchiellini⁷, B. Pollio⁸, E. Zanon⁹, G. Barillari¹⁰, A. Poz¹⁰, S. Sorella¹, S. Ligia¹, R. Mormile¹, E. Baldacci¹, G. Castaman¹¹, F. Peyvandi^12|13, C. Santoro¹ | ¹Hematology, Department of Translational and Precision Medicine, Sapienza University of Rome, Italy; ²Department of Molecular Biology, Sapienza University of Rome, Italy; ³Hemostasis and Thrombosis Unit, Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy; ⁴Hematology Unit, Azienda ULSS 8 Berica - San Bortolo Hospital, Vicenza, Italy; ⁵Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Italy; ⁶Coagulation Diseases Center, Transfusion Medicine Department - Azienda Sanitaria Universitaria Integrata del Trentino, Trento, Italy; ⁷Centro di Riferimento Regionale Malattie Emorragiche e Trombotiche dell'Adulto, Divisione di Ematologia, Università Città della Salute e della Scienza di Torino, Italy; ⁸SIMT Immunohematology and Transfusion Medicine Service, Diagnostic Department, A.O. Città della Salute e della Scienza, Torino, Italy; ⁹Department of Medicine, Haemophilia Centre, University Hospital of Padua, Italy; ¹⁰Center for Hemorrhagic and Thrombotic Diseases, General and University Hospital S. Maria della Misericordia, Udine, Italy; ¹¹Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze, Italy; ¹²IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milano, Italy; ¹³Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milano, Italy

  Mario Biglietto

  14-10-2026

  https://doi.org/10.4081/btvb.2026.680

  57

  PDF: 18

• PO032 | INHIBITION OF PLATELET ACTIVATION BY SMALL MOLECULE SYNTHETIC AGONISTS OF THE BILE ACID RECEPTOR: A NOVEL APPROACH TO ANTIPLATELET THERAPY L. Bury¹, E. Falcinelli¹, V. Fazzi¹, C. Tili¹, P. Gresele¹, S. Fiorucci² | ¹Department of Medicine and Surgery, Section of Internal and Cardiovascular Medicine; ²Section of Gastroenterology, University of Perugia, Italy

  Loredana Bury

  26-10-2026

  https://doi.org/10.4081/btvb.2026.848

  34

  PDF: 17
• 

  PO03 | HEPATIC FIBROSIS–DRIVEN TISSUE FACTOR EXPRESSION BY MALIGNANT CHOLANGIOCYTES IS ASSOCIATED WITH CANCER-ASSOCIATED THROMBOSIS AND POOR SURVIVAL IN INTRAHEPATIC CHOLANGIOCARCINOMA L. Fabris^1|2|3, Y. Frión-Herrera¹, C. Venturin^1|3, M. Cadamuro⁴, J. Gasparello⁵, C. M. Radu^1|2, M. Fassan^1|5, C. Mescoli⁶, U. Cillo^7|8, E. Gringeri^7|8, G. Zanus^7|9, E. Campello^1|2, M. Strazzabosco³, P. Simioni^1|2 | ¹Department of Medicine, University of Padua; ²Clinical Medicine 1 and Thrombotic and Haemorrhagic Disease Unit, and Haemophilia Center, Padua University-Hospital; ³Department of Internal Medicine, Digestive Disease Section, Liver Center, Yale University, New Haven, CT, USA; ⁴School of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy; ⁵Pathology Unit, Ca' Foncello Hospital, ULSS2 Marca Trevigiana, Treviso; ⁶Pathology Unit, Padua University-Hospital; ⁷Department of Surgery, Oncology and Gastroenterology, University of Padua; ⁸Hepatobiliary Surgery and Liver Transplantation Unit, Padua University-Hospital; ⁹General Surgery Unit, Ca' Foncello Hospital, ULSS2 Marca Trevigiana, Treviso, Italy

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.499

  528

  PDF: 103

• PO025 | CHARACTERIZATION OF PLATELET DYSFUNCTION IN NOONAN SYNDROME PATIENTS S. Sorrentino¹, I. Lazzareschi², A. Ferretti¹, R. Onesimo², A. Romano³, G. Zampino², C. Leoni², E. De Candia¹ | ¹UOS Piastrinopenie Congenite e Piastrinopatie, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy; ²UOC Pediatria, Fondazione Policlinico Universitario Agostino Gemelli IRCSS, Roma, Italy; ³UOC Oncologia Pediatrica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy

  Silvia Sorrentino

  26-10-2026

  https://doi.org/10.4081/btvb.2026.841

  42

  PDF: 20

• CO15 | Longitudinal coagulation profiling of individuals undergoing gender-affirming hormone therapy: the hyper-gender study A. Napolitano, E. Campello, A. Scala, C. Simion, C. Bulato, S. Gavasso, C. Samà, A. Benetti, S. Toffanin, G. Faggian, R. Scafa, A. Garolla, P. Simioni | First Chair of Internal Medicine, Department of Medicine, University Hospital of Padua; Unit of Andrology and Reproductive Medicine, Department of Medicine, University Hospital of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.219

  685

  PDF: 22

• PO017 | BEYOND IONIC STRENGTH: ANION EFFECTS ON FIBRIN CLOT FORMATION, STRUCTURE, AND MECHANICAL PROPERTIES C. Spoliti¹, T. Feller², F.L. Macrae², R.A.S. Ariëns², R. De Cristofaro^1|3, E. Di Stasio^4|5 | ¹Department of Translational Medicine and Surgery, Università Cattolica del Sacro Cuore, Roma, Italy; ²Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom; ³Hemorrhagic and Thrombotic Diseases Center, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; ⁴Department of Basic Biotechnological Sciences, Intensive Care and Perioperative Clinics, Università Cattolica del Sacro Cuore, Roma, Italy; ⁵Clinical Chemistry, Biochemistry and Molecular Biology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy

  Claudia Spoliti

  26-10-2026

  https://doi.org/10.4081/btvb.2026.833

  50

  PDF: 16

• CO02 | Hepatic fibrosis as predictor of cancer-associated thrombosis in patients with intrahepatic cholangiocarcinoma Y. Frion-Herrera^1,2, C. Venturin^1,3, M. Cadamuro⁴, J. Gasparello⁵, C.M. Radu¹, M. Fassan⁵, C. Mescoli⁶, U. Cillo⁷, E. Gringeri⁷, G. Zanus⁸, L. Fabris^1,3, P. Simioni¹ | ¹Clinical Medicine and Thrombotic and Haemorrhagic Disease Unit, and Haemophilia Center, Padua University-Hospital, Department of Medicine [DIMED], University of Padua, Italy; ²Department of Biology [DiBio], University of Padua, Italy; ³Department of Internal Medicine, Digestive Disease Section, Liver Center, Yale University, New Haven, CT, USA; ⁴School of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy; ⁵Department of Pathology Ca’ Foncello Hospital, ULSS2 Marca Trevigiana, Italy; ⁶Pathology Unit, Padua University-Hospital, Padua, Italy; ⁷Hepatobiliary Surgery and Liver Transplantation Unit, Padua University-Hospital, Department of Surgery, Oncology and Gastroenterology [DISCOG], University of Padua, Italy; ⁸General Surgery Unit, Ca’ Foncello Hospital, ULSS2 Marca Trevigiana, Department of Surgery, Oncology and Gastroenterology [DISCOG], University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.207

  729

  PDF: 30

• CO110 | FLOW-BASED WHOLE-BLOOD THROMBUS PROFILING DISCRIMINATES ANTITHROMBOTIC DRUG EFFECTS AND UNCOVERS PLATELET-DEPENDENT COAGULATION DEFECTS AFTER CARDIOPULMONARY BYPASS A. Foladore¹, S. Lattanzio¹, E. Baryshnikova², M. Anguissola², E. Lombardi³, M. Valvasori³, R. Vettori³, F. Agostini³, R. Tassan Toffola⁴, L. Rota¹, M. Ranucci², M. Mazzucato³ | ¹Sedicidodici s.r.l., Pordenone, Italy; ²IRCCS Policlinico San Donato, San Donato Milanese, Italy; ³Centro di Riferimento Oncologico (CRO) IRCCS, Aviano, Italy; ⁴Azienda Sanitaria Friuli Occidentale, Pordenone, Italy

  Mario Mazzucato

  26-10-2026

  https://doi.org/10.4081/btvb.2026.812

  52

  PDF: 15

• PO07 | Liver transplant in a case of congenital afibrinogenemia G. Murante^1,2,3, S. Bergonzi^1,2,3, C. Sella^1,2,3, F. Valeri^1,2, C. Dainese^1,2, A. Valpreda⁴, R. Pastorino^1,3, R. Romagnoli⁵, D. Patrono⁵, D. Cussa⁵, S. Martini⁶, B. Bruno^2,3, A. Borchiellini^1,2 | ¹Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Torino; ²Division of Hematology, AOU Città della Salute e della Scienza, University of Turin; ³Department of Molecular Biotechnology and Health Sciences, University of Turin; ⁴Central Laboratory Baldi and Riberi, AOU Città della Salute e della Scienza, Torino; ⁵General Surgery 2U - Liver Transplant Center, Molinette Hospital, AOU Città della Salute e della Scienza, Torino; ⁶SSD Hepatic insufficiency and Liver Transplant, AOU Città della Salute e della Scienza, Torino, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.269

  598

  PDF: 20

• PO111 | A RARE CASE OF ACUTE PROMYELOCYTIC LEUKAEMIA PRESENTING WITH A PURELY THROMBOTIC DISSEMINATED INTRAVASCULAR COAGULATION PHENOTYPE L. Colavolpe, M. Provisione, L. Appio, S. Tupputi, N. Mumoli | ASST Valle Olona, Busto Arsizio, VA, Italy

  Lucia Colavolpe

  26-10-2026

  https://doi.org/10.4081/btvb.2026.927

  36

  PDF: 17

• CO067 | ELUCIDATING THE EVIL RELATIONSHIP OF METABOLIC DYSFUNCTION–ASSOCIATED FATTY LIVER DISEASE WITH CARDIOVASCULAR COMORBIDITIES: THE COMPLEX INTERPLAY AMONG HYPERCOAGULABILITY, INFLAMMATION, AND LIVER FIBROSIS G. Gagliardi, E. Campello, A. Napolitano, B. Stocco, C. Di Gesù, G. Gobbo, I. Condonato, M. Allegra, G. Antonello, C. Portinari, C. Goffi, G. Camporese, P. Scarinzi, R. Pesavento, F. Bilora, M. Di Pascoli, C. Bulato, A. Montagna, D. Regazzo, A. Zambon, L. Fabris, P. Simioni | Department of Medicine, University of Padova, Italy

  Elena Campello

  26-10-2026

  https://doi.org/10.4081/btvb.2026.769

  62

  PDF: 18
• 

  Long-term persistence of high anti-PF4 antibodies titer in a challenging case of AZD1222 vaccine-induced thrombotic thrombocytopenia

  Luca Barcella, Chiara Ambaglio, Paolo Gritti, Francesca Schieppati, Varusca Brusegan, Eleonora Sanga, Marina Marchetti, Luca Lorini, Anna Falanga

  28-06-2023

  https://doi.org/10.4081/btvb.2023.72

  1288

  PDF: 452
• 

  A case of acquired factor XIII deficiency secondary to plasmablastic lymphoma

  Vincenzo Sammartano, Adele Santoni, Elisabetta Zappone, Paola Calzoni, Daniela Fineschi, Eleonora Franceschini, Federico Caroni, Anna Sicuranza, Monica Bocchia, Luca Puccetti

  09-03-2023

  https://doi.org/10.4081/btvb.2023.53

  1439

  PDF: 572

• PO083 | WOMEN AND HEMOPHILIA: ASSESSMENT OF THE BLEEDING PHENOTYPE – ANALYSIS OF THE BRESCIA COHORT N. Portesi, S. Pontoglio, G. Carracchia, G. Albrici, E. Bertoni, G. Martini | ASST Spedali Civili di Brescia, Italy

  Nicola Portesi

  26-10-2026

  https://doi.org/10.4081/btvb.2026.899

  43

  PDF: 18

• PO33 | Whole blood hypercoagulable profiles in patients with rheumatoid arthritis L. Spiezia¹, A. Giollo², C. Samà¹, A. Benetti¹, L. Di Luozzo², M. Salvato², A. Doria², P. Simioni¹ | ¹First Chair of Internal Medicine, Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, University Hospital of Padova; ²Rheumatology Unit, Department of Medicine, University Hospital of Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.296

  640

  PDF: 21

• CO21 | Viscoelastic testing in inherited bleeding disorders: a cross-sectional comparison between viscoelastic coagulation monitoring and rotational thromboelastometry C. Simion, C. Samà, C. Bulato, G. Gottardi, D. Regazzo, E. Campello, P. Simioni | Department of Medicine – DIMED, University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.227

  655

  PDF: 25

• PO080 | BEYOND STANDARD COAGULOPATHY: SEVERE FACTOR XIII DEFICIENCY AS THE HARBINGING SIGN OF ACUTE PROMYELOCYTIC LEUKEMIA L. Banov, G. Gazzelli, C. Vernarecci, F. Marotta, F. Giacopelli, B. Tappino, B. Antonioli, A.C. Molinari | IRCCS Istituto Giannina Gaslini Genova, Italy

  Angelo Claudio Molinari

  26-10-2026

  https://doi.org/10.4081/btvb.2026.896

  41

  PDF: 21

• PO25 | Baseline thrombin generation test does not predict thrombotic events in acute leukemia: a monocentric prospective study M. Biglietto, R. Mormile, M.L. Bisegna, A. Laganà, A. L. Faccini, A. Papa, E. Baldacci, C. Santoro, M.S. De Propris, A. Chistolini | Hematology, Department of Translational and Precision Medicine Sapienza University of Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.286

  664

  PDF: 20

• CO008 | ALLOSTATIC LOAD AND THE RISK OF ARTERIAL AND VENOUS VASCULAR EVENTS: A PROSPECTIVE ANALYSIS FROM THE MOLI-SANI STUDY T. Panzera¹, A. Di Castelnuovo¹, M. Bonaccio¹, S. Magnacca¹, A. De Curtis¹, F. Bracone¹, W. Ageno², C. Cerletti¹, M.B. Donati¹, G. de Gaetano¹, L. Iacoviello^1|3, S. Costanzo^1|4 | ¹Research Unit of Epidemiology and Prevention, IRCCS NEUROMED, Pozzilli, Italy; ²Department of Medicine, University of Padua, Padova, Italy; ³Department of Medicine and Surgery LUM University “Giuseppe Degennaro”, Casamassima, Italy; ⁴Department of Medicine and Surgery, University of Insubria, Varese, Italy

  Teresa Panzera

  26-10-2026

  https://doi.org/10.4081/btvb.2026.710

  128

  PDF: 29
• 

  Safety of COVID-19 mRNA vaccination in patients with history of acquired hemophilia A: a case series

  Luca Puccetti, Vincenzo Sammartano, Federico Caroni, Margherita Malchiodi, Paola Calzoni, Eleonora Franceschini, Lucrezia Galasso, Monica Bocchia

  17-10-2022

  https://doi.org/10.4081/btvb.2022.40

  3073

  PDF: 437

• PO019 | LONGITUDINAL COAGULATION PROFILING BY THROMBIN GENERATION AND CIRCULATING MICROVESISCLES OF INDIVIDUALS UNDERGOING GENDER-AFFIRMING HORMONE THERAPY E. Campello, A. Scala, A. Napolitano, C. Simion, C. Bulato, S. Toffanin, S. Gavasso, B. Serena, A. Montagna, A. Garolla, P. Simioni | Department of Medicine, University of Padova, Italy

  Elena Campello

  26-10-2026

  https://doi.org/10.4081/btvb.2026.835

  48

  PDF: 21

• CO-43 | VALIDATION OF THROMBIN GENERATION MEASUREMENT IN PLATELET-RICH PLASMA: EVOLUTION IN THE ST GENESIA^® SYSTEM F. Bocchi^1|2, R. Pastorino^1|2, G. Murante^1|2|3, S. Bergonzi^1|2|3, M. Capetta^1|2|3, F. Valeri^2|3, C. Dainese^2|3, A. Valpreda⁴, B. Bruno^1|3, A. Borchiellini^2|3 | ¹Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ²Regional Centre for Thrombotic and Hemorrhagic Diseases, AOU Città della salute e della Scienza di Torino, Italy; ³Division of Hematology, AOU Città della Salute e della Scienza, University of Turin, Italy; ⁴Central Lab Baldi and Riberi, AOU Città della salute e della Scienza di Torino, Italy

  Francesca Bocchi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.653

  54

  PDF: 17

• PO076 | ACQUIRED FACTOR V INHIBITOR WITH CONCOMITANT LUPUS ANTICOAGULANT: DIAGNOSTIC PITFALLS AND THERAPEUTIC CHALLENGES G. Gazzelli¹, Y. Azzanelli¹, C. Vernarecci¹, F. Marotta¹, F. Giacopelli¹, E. Cenni², V. Agostini², L. Banov¹, AC Molinari¹ | ¹IRCCS Istituto Giannina Gaslini, Italy; ²IRCSS AOM S. Martino Genova, Italy

  Angelo Claudio Molinari

  26-10-2026

  https://doi.org/10.4081/btvb.2026.892

  56

  PDF: 27

• PO22 | Early detection and management of PICC-related thrombosis in oncohematologic patients through serial ultrasound monitoring: a prospective observational study S. Laurenti, M. Schneeberger, G. Rosati, A. Pozzi, M. Padrini, R. Vacchelli, A. Morotti | University of Turin, AUO San Luigi Gonzaga, Orbassano (TO), Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.282

  659

  PDF: 34

• CO-85 | ACQUIRED HEMOPHILIA A IN LIVER CIRRHOSIS: BALANCING HEMOSTASIS BETWEEN HIGH HEMORRHAGIC AND THROMBOTIC RISKS N. Portesi, G. Martini | ASST Spedali Civili di Brescia, Italy

  Nicola Portesi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.695

  58

  PDF: 28
• 

  Expanding the genetic landscape of hereditary thrombophilia: classical defects, novel variants, and genomic perspectives. A narrative review

  Chiara Simion, Elena Campello, Walter Ageno, Paolo Simioni

  28-08-2026

  https://doi.org/10.4081/btvb.2026.427

  1240

  PDF: 159

  SUPPLEMENTARY FILES: 111

• PO10 | Clinical and laboratory features of long-Covid syndrome: a cross-sectional study of 1,337 Covid-19 survivors C. Ambaglio¹, S. V. Benatti², C. J. Tartari^1,3, L. Russo^1,3, S. Bolognini^1,3, C. Ticozzi¹, F. Schieppati¹, V. Brusegan¹, S. Venturelli², L. Barcella¹, M. Rizzi², M. Marchetti^1,3, A. Falanga^1,3 | ¹Department of Immunohematology and Transfusion Medicine, Papa Giovanni XXIII Hospital, Bergamo; ²Division of Infectious Diseases, Papa Giovanni XXIII Hospital, Bergamo; ³Department of Medicine and Surgery, University of Milan Bicocca, Monza, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.272

  666

  PDF: 23

• CO-83 | ACQUIRED FACTOR V DEFICIENCY IN A HIGH-THROMBOTIC-RISK PATIENT: DIAGNOSTIC DILEMMA AND SUCCESSFUL MANAGEMENT G. Gazzelli¹, L. Banov¹, Y. Azzanelli¹, C. Vernarecci¹, F. Marotta¹, F. Giacopelli¹, E. Cenni², V. Agostini², A.C. Molinari¹ | ¹IRCCS Istituto Giannina Gaslini, Italy; ²IRCSS AOM S. Martino, Genova, Italy

  Angelo Claudio Molinari

  14-10-2026

  https://doi.org/10.4081/btvb.2026.693

  66

  PDF: 27
• 

  Rationale and design of a study on D-dimer use to stratify patients after a first unprovoked venous thromboembolism for their risk of recurrence: extended low-dose Apixaban given only to patients with positive D-dimer results The Apidulcis study

  Gualtiero Palareti, Paolo Prandoni, Cristina Legnani, Emilia Antonucci, Serena Zorzi, Alberto Tosetto, Lorenza Bertù, Sophie Testa, Vittorio Pengo, Walter Ageno, Ida Martinelli, Benilde Cosmi, Eugenio Bucherini, Daniela Poli

  22-03-2022

  https://doi.org/10.4081/btvb.2022.10

  1895

  PDF: 572

  APPENDIX: 144

• PO128 | FROM SEVERE THROMBOSIS TO SUCCESSFUL PREGNANCIES: ORTHOTOPIC LIVER TRANSPLANTATION IN INHERITED AFIBRINOGENEMIA WITH BUDD–CHIARI SYNDROME G. Murante^1|2|6, S. Bergonzi^1|2|6, M. Capetta^1|2|6, F. Valeri^1|2, C. Dainese^1|2, A. Valpreda⁴, R. Pastorino^1|6, F. Bocchi^1|6, R. Romagnoli⁵, S. Martini³, B. Bruno^2|6, A. Borchiellini^1|2 | ¹Regional Centre for Hemorrhagic and Thrombotic Diseases; ²Division of Hematology; ³SSD Hepatic insufficiency and Liver Transplant; ⁴Central Lab. Baldi and Riberi; ⁵General Surgery 2U - Liver Transplant Center, Molinette Hospital, AOU Città della Salute e della Scienza di Torino, Italy; ⁶Dep. of Molecular Biotechnology and Health Sciences, University of Turin, Italy

  Giovanni Murante

  26-10-2026

  https://doi.org/10.4081/btvb.2026.944

  41

  PDF: 18
• 

  The expanded universe of thrombin: a comprehensive review of its hemostasis-independent roles and structure-function relationships

  Monica Sacco, Stefano Lancellotti, Antonietta Ferretti, Maria Basso, Leonardo Di Gennaro, Raimondo De Cristofaro

  28-08-2026

  https://doi.org/10.4081/btvb.2026.462

  453

  PDF: 138

• PO059 | HYPERCOAGULABILITY AND THROMBOTIC RISK IN MODERATE-TO-SEVERE OBSTRUCTIVE SLEEP APNEA: A PROSPECTIVE OBSERVATIONAL STUDY L. Spiezia¹, S. Carraro², E. Bicego¹, A. Napolitano¹, C. Samà¹, A. Benetti¹, B. Serena¹, R. Marchese Ragona², P. Simioni¹ | ¹Dipartimento di Medicina, Azienda Osp. Università di Padova, Italy; ²Dipartimento di Neuroscienze, Azienda Osp. Università di Padova, Italy

  Luca Spiezia

  26-10-2026

  https://doi.org/10.4081/btvb.2026.875

  36

  PDF: 23

• CO-82 | ACQUIRED SEVERE FACTOR XIII DEFICIENCY AS THE INITIAL PRESENTATION OF PAEDIATRIC ACUTE PROMYELOCYTIC LEUKAEMIA C. Vernarecci, G. Gazzelli, L. Banov, F. Marotta, F. Giacopelli, B. Tappino, B. Antonioli, A.C. Molinari | IRCCS Istituto Giannina Gaslini, Genova, Italy

  Angelo Claudio Molinari

  14-10-2026

  https://doi.org/10.4081/btvb.2026.692

  75

  PDF: 15