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Bleeding, Thrombosis and Vascular Biology

Editor-in-Chief: Giovanni de Gaetano, Italy | eISSN: 2785-5309

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  • The key to fibrinolysis and thrombolysis

    Roger Lijnen, Désiré Collen
    09-09-2025
    https://doi.org/10.4081/btvb.2025.368
    974
    PDF: 180
    HTML: 102
  • Persistence of functional anti-PF4 antibodies and neutrophil activation in vaccine-induced immune thrombotic thrombocytopenia

    Eleonora Petito, Anna Maria Mezzasoma, Emanuela Falcinelli, Chiara Conti, Erica De Candia, Raimondo De Cristofaro, Silvia Sorrentino, Gian Marco Podda, Mariangela Scavone, Anna Falanga, Marina Marchetti, Luca Barcella, Stefania Basili, Lucia Stefanini, Andrea Boccatonda, Laura Contino, Patrizia Sciancalepore, Igor Florio, Egidio Imbalzano, Rossella Marcucci, Angela Rogolino, Patrizia Noris, Marta Panella, Rita Santoro, Maria Costanza Turi, Gaetano Vaudo, Rosa Curcio, Paolo Gresele
    18-11-2025
    https://doi.org/10.4081/btvb.2025.400
    414
    PDF: 58
    HTML: 40
  • A commitment to global collaboration, welcoming international participation and advancing science for the benefit of patients

    Pantep Angchaisuksiri, Wolfram Ruf, Jeffrey Weitz, Sam Schulman, Guy A. Young
    01-07-2025
    https://doi.org/10.4081/btvb.2025.188
    1257
    PDF: 178
    HTML: 16
  • Diagnostic and management practices for inherited fibrinogen disorders: a nationwide survey of Italian Hemophilia Treatment Centers

    Renato Marino, Silvia Linari, Marzia Leotta, Antonio Coppola, Chiara Biasoli, Maria Elisa Mancuso, Flora Peyvandi, Cristina Santoro, Ezio Zanon, Rita Carlotta Santoro
    02-12-2025
    https://doi.org/10.4081/btvb.2025.372
    266
    PDF: 33
    HTML: 14
    Supplementary: 9
    Appendix: 6
  • Anticoagulation in obese patients: challenges and strategies

    Alice Lipari, Esmeralda Capristo, Antonietta Ferretti, Erica De Candia
    18-09-2025
    https://doi.org/10.4081/btvb.2025.174
    1091
    PDF: 174
    HTML: 91
    XML: 41
  • Long-term persistence of high anti-PF4 antibodies titer in a challenging case of AZD1222 vaccine-induced thrombotic thrombocytopenia

    Luca Barcella, Chiara Ambaglio, Paolo Gritti, Francesca Schieppati, Varusca Brusegan, Eleonora Sanga, Marina Marchetti, Luca Lorini, Anna Falanga
    28-06-2023
    https://doi.org/10.4081/btvb.2023.72
    847
    PDF: 263
  • PO22 | Early detection and management of PICC-related thrombosis in oncohematologic patients through serial ultrasound monitoring: a prospective observational study S. Laurenti, M. Schneeberger, G. Rosati, A. Pozzi, M. Padrini, R. Vacchelli, A. Morotti | University of Turin, AUO San Luigi Gonzaga, Orbassano (TO), Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.282
    389
    PDF: 0
  • Vaccine-induced immune thrombotic thrombocytopenia following ChAdOx1 nCoV-19 vaccine: report of two cases

    Rita Carlotta Santoro, Roberto Minici, Marzia Leotta, Mariapia Falbo, Lucia Concetta Elia, Francesca Leo, Antonella Ierardi, Alessandra Strangio, Simona Prejanò
    23-05-2022
    https://doi.org/10.4081/btvb.2022.23
    4006
    PDF: 0
  • The landscape of rare coagulation factor deficiency management in Italy: a national hemophilia center survey

    Silvia Linari, Renato Marino, Marzia Leotta, Antonio Coppola, Patrizia Di Gregorio, Augusto Bramante Federici, Flora Peyvandi, Cristina Santoro, Ezio Zanon, Rita Carlotta Santoro
    05-11-2025
    https://doi.org/10.4081/btvb.2025.369
    523
    PDF: 75
    HTML: 4
    Appendix: 36
  • Executive summary of the SISET position paper on the management of antithrombotic therapy in left ventricular thrombus

    Emanuele Valeriani, Arianna Pannunzio, Danilo Menichelli, Domenico Prisco, Walter Ageno, Daniele Pastori, Pasquale Pignatelli
    16-12-2025
    https://doi.org/10.4081/btvb.2025.401
    78
    PDF: 10
    HTML: 2
  • Thrombin generation assay in COVID-19 patients shows a hypocoagulable pattern

    Giovanni L. Tiscia, Donatella Colaizzo, Antonio De Laurenzo, Filomena Cappucci, Lucia Fischetti, Elena Chinni, Mario Mastroianno, Giovanni Favuzzi, Massimo Carella, Elvira Grandone
    22-10-2024
    https://doi.org/10.4081/btvb.2024.145
    2138
    PDF: 328
    Supplementary: 211
  • Attitude to clinical research among health professionals affiliated with the Italian Federation of Centers for the Diagnosis of Thrombotic Disorders and the Surveillance of the Antithrombotic Therapies (FCSA)

    Daniela Poli, Riccardo Tartaglia, Doris Barcellona , Paolo Bucciarelli , Antonio Ciampa, Elvira Grandone, Giuseppe Malcangi, Giuseppe Rescigno, Vincenzo Toschi, Sophie Testa, Alessandro Squizzato
    21-03-2023
    https://doi.org/10.4081/btvb.2023.59
    820
    PDF: 279
  • Cancer complicated by thrombosis and thrombocytopenia: still a therapeutic dilemma

    Yishi Tan, Marc Carrier, Nicola Curry, Michael Desborough, Kathryn Musgrave, Marie Scully, Tzu-Fei Wang, Mari Thomas, Simon J. Stanworth
    16-05-2024
    https://doi.org/10.4081/btvb.2024.115
    1007
    PDF: 401
  • 29th National Conference of the Italian Society for the Study of Hemostasis and Thrombosis, 2025

    Guest Editor: Valerio De Stefano
    22-10-2025
    https://doi.org/10.4081/btvb.2025.408
    567
  • https://pixabay.com/users/geralt-9301/?utm_source=link-attribution&utm_medium=referral&utm_campaign=image&utm_content=1571860

    Artificial intelligence and machine learning in hemostasis and thrombosis

    Paolo Gresele
    30-12-2023
    https://doi.org/10.4081/btvb.2023.105
    3011
    PDF: 626
  • Management of anticoagulation in atrial fibrillation patients in Italy: insight from the Atrial Fibrillation-Survey on Anticoagulated Patients Register (AF-START)

    Daniela Poli, Walter Ageno, Emilia Antonucci, Salvatore Bradamante, Eugenio Bucherini, Paolo Chiarugi, Antonio Chistolini, Benilde Cosmi, Anna Falanga, Antonio Insana, Domenico Lione, Rosa Maria Lombardi, Giuseppe Malcangi, Rossella Marcucci, Giuliana Martini, Lucilla Masciocco, Carmelo Paparo, Daniele Pastori, Simona Pedrini, Vittorio Pengo, Pasquale Pignatelli, Andrea Toma, Sophie Testa, Gualtiero Palareti
    27-06-2023
    https://doi.org/10.4081/btvb.2023.84
    1580
    PDF: 363
    Supplementary File: 189
  • Allopurinol-induced acquired von Willebrand syndrome

    Juan Eirís, Marina Suárez-Terrón, Pablo Granados, David Martínez-Campuzano, Ana Rosa Cid, Saturnino Haya, Santiago Bonanad
    25-10-2023
    https://doi.org/10.4081/btvb.2023.88
    1858
    PDF: 252
  • Pathways for lower extremity superficial vein thrombosis management in an academic medical center

    Gisoo Imani, Aaron Wilson, Sara Vazquez, Daniel M. Witt
    24-03-2025
    https://doi.org/10.4081/btvb.2025.155
    450
    PDF: 126
  • Descriptive analysis of patients positive for anti-phospholipid antibodies included in two Italian registries

    Vittorio Pengo, Luca Sarti, Emilia Antonucci, Stefania Di Agostino, Elisa Bison, Gentian Denas, Daniela Poli, Pier Luigi Meroni, Roberto Gerli, Antonella Radice, Gualtiero Palareti, on behalf of FIRMA group and START collaborators
    12-10-2023
    https://doi.org/10.4081/btvb.2023.92
    1014
    PDF: 313
  • PO79 | Trying to hit the hit in the shadow of renal failure: a complex case managed with danaparoid S. Chessa1,2, M. Anedda2, M.V. Cherchi2, M. Vacca1,2, M. Caboni2, J. Pilia2, A.M. Bussu2, M. Mantega2, G. Costanzo1, D. Firinu1, S. Del Giacco1, A. Mameli3, D. Barcellona3 | 1Department of Medical Science and Public Health, University of Cagliari; 2Internal Medicine, ASL Sulcis, PO Sirai, Carbonia; 3Department of Medical Sciences and Public Health, Hemostasis and Thrombosis Unit, University of Cagliari and AOU of Cagliari, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.348
    405
    PDF: 0
  • PO59 | Efficacy and safety of different anticoagulant treatment regimens for isolated internal jugular vein thrombosis: a case series A. Pannunzio1, E. Valeriani1, I.M. Palumbo1, S. Marucci2, D. Menichelli1, D. Pastori2, P. Pignatelli2 | 1Department of General Surgery and Surgical Specialty, Sapienza University of Roma; 2Department of Clinical, Internal Medicine, Anaesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.328
    375
    PDF: 0
  • When a feminist platelet went to the convention of prostaglandins and thromboxanes

    Giovanni de Gaetano
    04-11-2025
    https://doi.org/10.4081/btvb.2025.412
    592
    PDF: 74
    HTML: 34
    Italian version: 51
  • CO12 | Left internal carotid artery thrombosis in a patient with antiphospholipid antibody syndrome successfully treated with eculizumab A. Hoxha1, L. Nico2, F. Viaro3, L. Fabris1, Y.F. Herrera1, M. Munari4, C. Baracchini3, F. Causin2, P. Simioni1 | 1Internal Medicine Unit, Thrombotic and Haemorrhagic Centre, Department of Medicine - DIMED, University of Padua; 2Neuradiology Unit, University Hospital of Padua; 3Stroke Unit, Neurology Department, University of Padua; 4Intensive Care Unit, University Hospital of Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.216
    412
    PDF: 0
  • PO37 | Single centre experience on anticoagulation in carriers of non-mild inherited thrombophilia: direct oral anticoagulants (DOAC) efficacy and safety M. D’uva1,2, G. La Barba1, G. Montanaro1, M. Di Ianni1,2, P. Ranalli1,2 | 1Hematology Unit, S. Spirito Hospital, Pescara; 2Department of Medicine and Aging Sciences, D’Annunzio University, Chieti, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.300
    374
    PDF: 0
  • PO36 | Venous stenting for symptomatic iliac thrombosis: five-years experience of single center I. Nichele1, G. Marchesini1, L. Boi2, G. Carli1, A. Tosetto1 | 1Hemophilia and Thrombosis Center, Hematology Department, S. Bortolo Hospital, Vicenza; 2Radiology Department, Ospedale Ca’ Foncello, Treviso, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.299
    369
    PDF: 0
  • PO31 | Comparative analysis of anticoagulant therapy in patients over 90 years old: vitamin K antagonists versus direct oral anticoagulants G. Sottilotta1, P. Arrigo2, S. Cuzzocrea1, D. Megalizzi1, F. Luise3 | 1UOSD Microcitemie, Emostasi e Trombosi, Grande Ospedale Metropolitano di Reggio Calabria; 2Associazione Italiana Pazienti Anticoagulati, Sezione di Reggio Calabria; 3Laboratorio Analisi. Grande Ospedale Metropolitano di Reggio Calabria, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.292
    369
    PDF: 0
  • Thrombosis and hemostasis at the University of Padua: a reappraisal on the occasion of its 800th year of history

    Paolo Simioni, Vittorio Pengo, Paolo Prandoni
    07-11-2022
    https://doi.org/10.4081/btvb.2022.52
    2297
    PDF: 285
  • PO76 | Thrombosis associated with midline in autoimmune patient: a case report on the use of apixaban in a real-world setting M.V. Cherchi, M. Anedda, S. Che, M. Vacca, M. Caboni, M. Mantega | Department of Internal Medicine, ASL Sulcis, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.345
    376
    PDF: 0
  • Successful treatment of aortic arch mural thrombosis with low-dose, ultra-slow-flow thrombolysis: a case report and literature review

    Rosina Albisinni, Tommaso Marrazzo, Arta Karruli, Sabrina Manduca, Giuseppe Nobile, Nicola Galdieri, Marisa De Feo
    24-10-2022
    https://doi.org/10.4081/btvb.2022.44
    975
    PDF: 245
  • PO38 | Rates of hemorrhagic events and hemodialysis circuit thrombosis in patients with end-stage renal disease on hemodialytic treatment receiving a factor-XI inhibitor: a systematic review and meta-analysis D. Santagata, G. Barbui, M.P. Donadini, A. Squizzato | Department of Medicine and Surgery, Research Center on Thromboembolic Disorders and Antithrombotic Therapies, University of Insubria, Varese and Como, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.301
    374
    PDF: 0
  • CO04 | Direct oral anticoagulants in antiphospholipid syndrome: a single center real-life experience A. Hoxha1, E. Campello1, F. Ahmad2, L. Spiezia1, P. Scarinzi1, G. Gobbo1, S. Gavasso1, F. Sartorello1, C. Simion1, E. Zanon1, P. Simioni1 | 1Internal Medicine Unit, Thrombotic and Haemorrhagic Centre, Department of Medicine - DIMED; 2Department of Statistical Sciences) University of Padova, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.209
    477
    PDF: 0
  • PO63 | Atypical venous thrombosis in young patient with systemic lupus erythematosus and high-risk APL profile: provoked or not? E. Marrone, A. Parisi, G. Di Monda, F. Gallucci, D. Morelli, C. Romano, U. Malgeri, D. D’Auria, P. Morella | Internal Medicine Unit 3, Cardarelli Hospital, Naples, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.332
    361
    PDF: 0
  • Stroke in women: anticoagulation in a complicated puzzle

    Francesco Marongiu, Elvira Grandone, Silvia Marongiu, Antonella Mameli, Doris Barcellona
    26-08-2024
    https://doi.org/10.4081/btvb.2024.137
    1343
    PDF: 321
  • Still unmet problems with low molecular weight heparin prophylaxis of venous thromboembolism. An Italian survey

    Stefania Cavazza, Gualtiero Palareti*
    03-10-2025
    https://doi.org/10.4081/btvb.2025.177
    757
    PDF: 119
    HTML: 66
    Supplementary: 47
  • The use of creatine and the development of deep vein thrombosis. A scoping review

    Kartik Akkihal, Thomas Varkey, James Kelbert
    18-11-2024
    https://doi.org/10.4081/btvb.2024.142
    6072
    PDF: 374
    Supplementary: 141
  • PO81 | Direct oral anticoagulants in atypical site vein thrombosis: a single centre experience focused on cancer patients U. Mazzarelli1, A. Guida1, L. Agrelli1, M. Amato1, R. Guarrasi2, L. Santaniello2, C. Cardamone1, P. Vitale1, M. Triggiani1 | 1Centro per le Malattie Emorragiche Congenite e Malattie Trombotiche UOC Clinica Immunologica e Reumatologica AOU S. Giovanni di Dio e Ruggi d’Aragona, Salerno; 2UOC Clinica Oncologica AOU S. Giovanni di Dio e Ruggi d’Aragona, Salerno, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.350
    440
    PDF: 0
  • PO91 | Disseminated intravascular coagulation with deep vein thrombosis in a frail patient: an extreme manifestation triggered by sepsis during SGLT2i therapy M. Vacca1, M.V. Cherchi1, S. Che1, G.A.M.L. Costanzo2, D. Firinu2, M. Mantega1, S. Del Giacco2 | 1Ospedale Sirai, ASL Sulcis, 2Università degli Studi di Cagliari, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.361
    466
    PDF: 0
  • PO80 | Heparin-induced thrombocytopenia: a monocentric experience with danaparoid L. D’Innocenzo, S. Sorrentino, M. De Siati, A. Ferretti, E. De Candia | Unit of Haemostasis and Thrombosis Diseases, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.349
    443
    PDF: 0
  • PO35 | Cerebral veins thrombosis in patients with and without myeloproliferative neoplasm: a real life retrospective monocentric study I. Bertozzi, M.T. Sartori, M. Zerbinati, G. Libralon, A. Galbiati, P. Simioni | First Medical Clinic, Department of Medicine - DIMED, Università degli Studi di Padova, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.298
    359
    PDF: 0
  • Identifying novel biomarkers using proteomics to predict cancer-associated thrombosis

    Maria J. Fernandez Turizo, Rushad Patell, Jeffrey I. Zwicker
    16-05-2024
    https://doi.org/10.4081/btvb.2024.120
    1146
    PDF: 510
  • Recent advances in classic heparin-induced thrombocytopenia (HIT), autoimmune HIT, spontaneous HIT, and vaccine-induced immune thrombotic thrombocytopenia

    Bianca Clerici, Mariangela Scavone, Gian Marco Podda
    20-06-2024
    https://doi.org/10.4081/btvb.2024.127
    2318
    PDF: 607
  • CO06 | Recurrences of catheter associated upper extremity deep vein thrombosis in cancer: a two year prospective study with enoxaparin M. Sartori, A. Trentini, S. Cavara, L. Borgese, M. Soldati, B. Cosmi | Angiology and Blood Coagulation Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.210
    430
    PDF: 0
  • PO28 | Long term effectiveness and safety of venous thromboembolism with fondaparinux: data from the start registry I.M. Palumbo1, E. Valeriani1,2, A. Pannunzio1, S. Marucci3, D. Menichelli1, D. Pastori3,4, P. Pignatelli3 | 1Department of General Surgery and Surgical Specialty, Sapienza University of Roma; 2Department of Infectious Disease, Azienda Ospedaliero-Universitaria Policlinico Umberto I, Roma; 3Department of Clinical Internal, Anaesthesiologic and Cardiovascular Sciences, Sapienza University of Roma, Roma; 4IRCCS NeuRomad, Pozzilli, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.289
    385
    PDF: 0
  • CO05 | Long-term management of upper extremity catheter-related thrombosis in female patients with cancer: a retrospective cohort study Chiara Cavallaro1,2, Paolo Santini1,2, Laura Leoni3, Carolina Mosoni1,2, Silvia D’Ambrosio1,2, Francesco Mancinetti1,2, Nicola Coletta1,2, Michela Iorio1,2, Angelo Porfidia1,2, Alessandro D’Errico1,2, Rosa Talerico1,2, Roberto Pola1,2 | 1Department of Aging, Orthopedic, and Rheumatologic Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome; 2Università Cattolica del Sacro Cuore, Rome; 3Vita-Salute University, San Raffaele Hospital IRCCS, Milan, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.309
    429
    PDF: 0
  • Rationale and design of a study on D-dimer use to stratify patients after a first unprovoked venous thromboembolism for their risk of recurrence: extended low-dose Apixaban given only to patients with positive D-dimer results The Apidulcis study

    Gualtiero Palareti, Paolo Prandoni, Cristina Legnani, Emilia Antonucci, Serena Zorzi, Alberto Tosetto, Lorenza Bertù, Sophie Testa, Vittorio Pengo, Walter Ageno, Ida Martinelli, Benilde Cosmi, Eugenio Bucherini, Daniela Poli
    22-03-2022
    https://doi.org/10.4081/btvb.2022.10
    1384
    PDF: 417
    APPENDIX: 94
  • PO92 | Challenging management of portal vein thrombosis in a cirrhotic patient on hormone therapy after breast cancer L. Jr Valletta, C. De Luca, M. Aversano, C. Caputo, E. Cimino, P. Conca, A. Tufano, M.D. Di Minno | AOU Federico II Napoli, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.362
    398
    PDF: 0
  • Is non-alcoholic fatty liver disease a prothrombotic risk factor?

    Niccolò Bitto, Vincenzo La Mura, Anna Ludovica Fracanzani, Armando Tripodi
    19-05-2023
    https://doi.org/10.4081/btvb.2023.81
    804
    PDF: 253
  • PO72 | Fondaparinux in patient with active tuberculosis T. Marrazzo1, R. Parrella2, A. Botta2, A. Pontarelli2, M.P. Ursi3, A. Karruli4, R. Albisinni5 | 1UOC Medicina Interna e dei Trapianti, Ospedale Monaldi, Napoli, Italy; 2UOC Malattie Infettive ad Indirizzo Respiratorio, Ospedale Cotugno Azienda dei Colli, Napoli, Italy; 3UOC MECAU Ospedale CTO Azienda dei Colli, Napoli, Italy; 4Malattie Infettive e Tropicali, Ospedale di Tirana, Albania; 5UOC CCH Generale, Ospedale Monaldi Azienda dei Colli, Napoli, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.341
    378
    PDF: 0
  • Diagnosis and management of abnormal uterine bleeding in adolescence An expert Consensus Statement of SIGO (Italian Society of Gynecology and Obstetrics) and SISET (Italian Society for the Study of Hemostasis and Thrombosis)

    Roberto Mario Santi, Annamaria Fulghesu, Ezio Zanon, Erica De Candia, Elvira Grandone, Giancarlo Di Renzo, Claudia Succu, Valentina Tosto, Vincenzina Bruni, Paolo Gresele
    08-05-2024
    https://doi.org/10.4081/btvb.2024.106
    1906
    PDF: 528
  • Distal deep vein thrombosis: is there a way out of this dark forest?

    Matteo Guarascio, Gerardo Nicola Pititto, Alessia Abenante, Marco Paolo Donadini
    04-09-2024
    https://doi.org/10.4081/btvb.2024.129
    1140
    PDF: 318
  • New drugs, old problems: immune checkpoint inhibitors and cancer-associated thrombosis

    Mehrie H. Patel, Alok A. Khorana
    16-05-2024
    https://doi.org/10.4081/btvb.2024.113
    806
    PDF: 417
  • CS01 | Elucidating the evil relationship of metabolic dysfunction–associated fatty liver disease with cardiovascular comorbidities: the complex interplay among hypercoagulability, inflammation and liver fibrosis G. Gagliardi, E. Campello, A. Napolitano, B. Stocco, C. Di Gesù, G. Gobbo, I. Condonato, M. Allegra, G. Camporese, P. Scarinzi, R. Pesavento, F. Bilora, C. Bulato, A. Benetti, C. Samà, C. Portinari, G. Antonello, C. Goffi, L. Di Daniel, A. Zambon, L. Fabris, P. Simioni | First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.196
    526
    PDF: 0
  • CO07 | Real word management of anticoagulant therapy in brain metastasis: moving toward a multidisciplinary approach in complex cases E. Lotti1, C. Manneschi2, S. Fancelli2, F. Scolari1, F. Crudele1, D. Poli1, M. Berteotti1, D. Rossini3, S. Pillozzi2, L. Antonuzzo2,3, R. Marcucci1,3 | 1Disease Unit, Careggi University Hospital, Firenze; 2Oncology Unit, Careggi University Hospital, Firenze; <sup>3</sup>Department of Experimental and Clinical Biomedical Sciences, University of Firenze, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.211
    440
    PDF: 0
  • Clinical and radiological characteristics of cerebral vein thrombosis: a retrospective study

    Mosaad Almegren
    12-10-2023
    https://doi.org/10.4081/btvb.2023.85
    753
    PDF: 217
  • From rare to aware: confronting Lemierre syndrome

    Silvia Cardi, Filippo Catalani, Luca Valerio, Stefano Barco
    21-10-2024
    https://doi.org/10.4081/btvb.2024.147
    2130
    PDF: 396
  • Welcome to the 12th International Conference on Thrombosis and Hemostasis Issues in Cancer! Proceedings

    Anna Falanga, Benjamin Brenner, Alok A. Khorana
    16-05-2024
    https://doi.org/10.4081/btvb.2024.138
    1558
    PDF: 422
  • The introduction of the international normalized ratio as a breakthrough event in the history of thrombosis

    Armando Tripodi
    23-01-2025
    https://doi.org/10.4081/btvb.2025.169
    966
    PDF: 273
  • Trends and updates on the epidemiology of cancer-associated thrombosis: a systematic review

    Ang Li, Emily Zhou
    16-05-2024
    https://doi.org/10.4081/btvb.2024.108
    1204
    PDF: 517
  • PO73 | False-positive CT diagnosis of DVT in a patient with severe venous sequelae: a case of bilateral cellulitis L. Jr Valletta, C. De Luca, M. Aversano, C. Caputo, G. Chiarelli, R. Russo, E. Cimino, P. Conca, A. Tufano, G. Iannuzzo, V. Mallardo, M.N.D. Di Minno | AOU Federico II, Napoli, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.342
    411
    PDF: 0
  • Patient and public involvement in cancer-associated thrombosis research: necessary or glorified tokenism?

    Simon Noble
    16-05-2024
    https://doi.org/10.4081/btvb.2024.125
    1451
    PDF: 350
  • PO07 | Liver transplant in a case of congenital afibrinogenemia G. Murante1,2,3, S. Bergonzi1,2,3, C. Sella1,2,3, F. Valeri1,2, C. Dainese1,2, A. Valpreda4, R. Pastorino1,3, R. Romagnoli5, D. Patrono5, D. Cussa5, S. Martini6, B. Bruno2,3, A. Borchiellini1,2 | 1Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Torino; 2Division of Hematology, AOU Città della Salute e della Scienza, University of Turin; 3Department of Molecular Biotechnology and Health Sciences, University of Turin; 4Central Laboratory Baldi and Riberi, AOU Città della Salute e della Scienza, Torino; 5General Surgery 2U - Liver Transplant Center, Molinette Hospital, AOU Città della Salute e della Scienza, Torino; 6SSD Hepatic insufficiency and Liver Transplant, AOU Città della Salute e della Scienza, Torino, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.269
    354
    PDF: 0
  • Artificial intelligence, platelets and aspirin

    Giovanni de Gaetano
    15-03-2024
    https://doi.org/10.4081/btvb.2024.130
    640
    PDF: 260
  • Evaluation of Coaguchek® Pro II coagulation testing device performance to assess direct oral anticoagulant action. The DOAC-CHECK study

    Cristina Legnani, Michela Cini, Sophie Testa, Alberto Tosetto, Claudia Dellanoce, Stefania Bellesso, Giuseppe Carli, Ilaria Nichele, Laura Lissandrini, Serena Zorzi, Emilia Antonucci, Gualtiero Palareti
    01-12-2022
    https://doi.org/10.4081/btvb.2022.37
    1768
    PDF: 353
  • At the age of three

    Giovanni de Gaetano, Chiara Cerletti
    16-12-2024
    https://doi.org/10.4081/btvb.2024.166
    567
    PDF: 118
  • Machine learning in cancer-associated thrombosis: hype or hope in untangling the clot

    Rushad Patell, Jeffrey I. Zwicker, Rohan Singh, Simon Mantha
    16-05-2024
    https://doi.org/10.4081/btvb.2024.123
    1838
    PDF: 546
  • Tailored therapy with turoctocog alfa pegol according to patient’s lifestyle and hemorrhagic phenotype: from clinical trial to real-life

    Ilaria Nichele, Giuseppe Carli, Alberto Tosetto
    22-04-2024
    https://doi.org/10.4081/btvb.2024.104
    714
    PDF: 199
  • PO15 | Venous thromboembolism risk associated with midline catheters and peripherally inserted central catheters: a systematic review and meta-analysis D. Santagata1, F. Subri1, F. Dentali1,2, M.P. Donadini1, I. Giarretta2 | 1Department of Medicine and Surgery, Research Center on Thromboembolic Disorders and Antithrombotic Therapies, University of Insubria, Varese and Como; 2Department of Internal Medicine, Ospedale di Circolo and Fondazione Macchi, Varese, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.276
    351
    PDF: 0
  • A message of science, peace and gratitude

    Giovanni de Gaetano, Chiara Cerletti
    02-12-2025
    https://doi.org/10.4081/btvb.2025.420
    290
    PDF: 20
  • PO87 | Intravascular leiomyomatosis extending to the right atrium: a case report with a multidisciplinary management M. Iorio1,2, C. Cavallaro1,2, E. Butera1,2, R. Talerico1,2, A. Gasbarrini2,3, R. Pola1,2 | 1Department of Aging, Orthopedic, and Rheumatologic Sciences, Agostino Gemelli Polyclinic Foundation Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma; 2Università Cattolica del Sacro Cuore, Roma; 3Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.357
    428
    PDF: 0
  • Remembering the XXVI SISET Congress and the 50th anniversary of its foundation, 2020

    Armando Tripodi
    17-01-2025
    https://doi.org/10.4081/btvb.2025.171
    1316
    PDF: 238
  • PO17 | Implementation and initial validation of a new teaching and assessment platform for experts in haemostasis and thrombosis A. Galbiati, S. Sandro, E. Campello, P. Simioni | Università degli Studi di Padova, Clinica Medica 1 - Malattie Trombotiche ed Emorragiche, Dipartimento di Medicina DIMED, Padova, Italy

    05-08-2025
    https://doi.org/10.4081/btvb.2025.314
    290
  • New perspectives for prevention of the post-thrombotic syndrome

    Paolo Prandoni
    22-03-2022
    https://doi.org/10.4081/btvb.2022.20
    1868
    PDF: 507
  • Factor XI inhibitors: a new option for the prevention and treatment of cancer-associated thrombosis

    Marcello Di Nisio, Matteo Candeloro, Nicola Potere, Ettore Porreca, Jeffrey I. Weitz
    16-05-2024
    https://doi.org/10.4081/btvb.2024.118
    1267
    PDF: 514
  • PO83 | A case of deep vein thrombosis in a patient with systemic mastocytosis M. Leotta, A. Ierardi, A. Strangio, R C. Santoro | UO Emofilia, Emostasi e Trombosi, AOU R Dulbecco, Catanzaro

    22-10-2025
    https://doi.org/10.4081/btvb.2025.352
    427
    PDF: 0
  • How to manage antithrombotic treatments in thrombocytopenic patients with cancer. Comments on the European Haematology Association guidelines

    Anna Falanga, Hugo Ten Cate, Bianca Rocca
    27-01-2023
    https://doi.org/10.4081/btvb.2023.60
    902
    PDF: 373
  • PO94 | The use of antidepressant drugs and benzodiazepine hypnotics as an unusual risk factor for VTE G. Chiarelli, F. Strano, P. Conca, P. Rufolo, M. G. Mazzone, R. Russo, L. Jr Valletta, G. D’Errico, C. De Luca, E. Cimino, A. Tufano, M.N.D. Di Minno | Department of Clinical Medicine and Surgery, Federico II University of Naples, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.364
    436
    PDF: 0
  • Comments on “Safe and effective anticoagulation use: case studies in anticoagulation stewardship”

    Marco Marietta, Giancarlo Castaman
    01-07-2025
    https://doi.org/10.4081/btvb.2025.180
    1490
    PDF: 438
  • PO56 | Safety of anticoagulant treatment in patients with splanchnic vein thrombosis and history of portal hypertension-related bleeding R. Talerico1, S. Pellegrino1, A. Plessier2, F.R. Ponziani3, A. Porfidia1, F. Landi1, A. Gasbarrini3, R. Pola1, F. Santopaolo3 | 1Department of Geriatric, Orthopedic, and Rheumatologic Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy; 2Université de Paris, AP-HP, C, DMU DIGEST, Centre de Référence des Maladies Vasculaires du Foie, FILFOIE, ERN RARE-LIVE. Centre de recherche sur l’inflammation, Inserm, Paris, France; 3Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.325
    354
    PDF: 0
  • CO38 | Management of pregnancy, delivery, and postpartum in Italian carriers and women with hemophilia A and B S. Linari1, B. Pollio2, A. Ferretti3, M. Napolitano4, E. Grandone5, S. Siboni6, Ab. Aru7, E. Bertoni8, C. Biasoli9, I. Cantori10, P. Di Gregorio11, G. Lassandro12, G. Sottilotta13, A. Strangio14, Mr. Villa15, A. Rocino16, G. Castaman1 | 1Center for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze; 2Regional Reference Center for Inherited Bleeding and Thrombotic Disorders, Transfusion Medicine, Regina Margherita Children Hospital, Turin; 3Center for Hemorrhagic and Thrombotic Diseases, IRCCS A. Gemelli University Hospital Foundation, Roma; 4Department of Health Promotion, Maternal-Childhood, Internal Medicine of Excellence G. D’Alessandro, University of Palermo; 5Thrombosis and Hemostasis Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo; 6Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan; 7Pediatric Onco-Hematology Center, Microcitemico Hospital Cagliari; 8Pediatric Oncohematology and Bone Marrow Transplant “BMT” Unit, Children’s Hospital, Spedali Civili, Brescia; 9Hemophilia and Transfusion Center, Bufalini Hospital, Cesena; 10Hemophilia Center, Department of Transfusion Medicine, Hospital of Macerata; 11Transfusion Medicine Department, SS. Annunziata Hospital, Chieti; 12B. Trambusti General and Specialised Pediatrics Unit, Giovanni XXIII Hospital, University of Bari; 13Hemophilia Center, Grande Ospedale Metropolitano, Reggio Calabria; 14Center for Hemorrhagic and Thrombotic Disorders, Pugliese Ciaccio Hospital, Catanzaro; 15Hemophilia and Thrombosis Center, Haematology Unit, Ospedale del Mare Hospital, Naples; 16Past President of the Italian Association of Hemophilia Centers, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.245
    353
    PDF: 0
  • PO82 | Retrospective application of the TH2 score in a multicenter cohort of ITP patients: a reliable predictive tool or a score in need of refinement? C. Giubbilei1, M. Defina2, S. Rosati3, M. Rocco3, A. Votto4, F. Simonetti5, F. Paoletti6, V. Carrai1 | 1Hematology Unit, AOU Careggi; 2Hematology unit AOU Senese; 3Hematology Unit Azienda Sanitaria Toscana Centro; 4Hematology Unit, AOU Pisana; 5Hematology Unit, Ospedale Versilia; 6Hematology Unit, Azienda Sanitaria Nord Ovest, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.351
    380
    PDF: 0
  • CO02 | Hepatic fibrosis as predictor of cancer-associated thrombosis in patients with intrahepatic cholangiocarcinoma Y. Frion-Herrera1,2, C. Venturin1,3, M. Cadamuro4, J. Gasparello5, C.M. Radu1, M. Fassan5, C. Mescoli6, U. Cillo7, E. Gringeri7, G. Zanus8, L. Fabris1,3, P. Simioni1 | 1Clinical Medicine and Thrombotic and Haemorrhagic Disease Unit, and Haemophilia Center, Padua University-Hospital, Department of Medicine [DIMED], University of Padua, Italy; 2Department of Biology [DiBio], University of Padua, Italy; 3Department of Internal Medicine, Digestive Disease Section, Liver Center, Yale University, New Haven, CT, USA; 4School of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy; 5Department of Pathology Ca’ Foncello Hospital, ULSS2 Marca Trevigiana, Italy; 6Pathology Unit, Padua University-Hospital, Padua, Italy; 7Hepatobiliary Surgery and Liver Transplantation Unit, Padua University-Hospital, Department of Surgery, Oncology and Gastroenterology [DISCOG], University of Padua, Italy; 8General Surgery Unit, Ca’ Foncello Hospital, ULSS2 Marca Trevigiana, Department of Surgery, Oncology and Gastroenterology [DISCOG], University of Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.207
    483
    PDF: 0
  • Gene therapy for hemophilia B

    Pier Mannuccio Mannucci
    12-12-2025
    https://doi.org/10.4081/btvb.2025.425
    279
    PDF: 11
    HTML: 0
  • A nitric oxide-donor pravastatin hybrid drug exerts antiplatelet and antiatherogenic activity in mice

    Stefania Momi, Giuseppe Guglielmini, Giulia Ciarroca Taranta, Elisa Giglio, Angela Monopoli, Paolo Gresele
    23-05-2022
    https://doi.org/10.4081/btvb.2022.19
    4854
    PDF: 343
  • CO10 | Multidimensional risk assessment of venous thromboembolism: an observational study comparing the Padua prediction score, Barthel index, and quality of life in hospitalized patients A. Mameli, S. Cornacchini, P. Schirru, F. Marongiu, D. Barcellona | Hemostasis and Thrombosis Unit, University of Cagliari, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.214
    450
    PDF: 0
  • PO53 | Effectiveness and safety of DOACS in patients with renal transplantation A. Ierardi, A. Strangio, M. Leotta, R C. Santoro | UO Emofilia, Emostasi e Trombosi, AOU Renato Dulbecco, Catanzaro, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.322
    385
    PDF: 0
  • Medicine at the crossroads of science, compassion and ethical responsibility

    Maria Benedetta Donati
    12-12-2025
    https://doi.org/10.4081/btvb.2025.423
    256
    PDF: 11
    HTML: 2
  • PO43 | Extended treatment with reduced dose of direct oral anticoagulants in patients with venous thromboembolism: a retrospective study A. Pannunzio1, E. Valeriani1, I.M. Palumbo1, D. Menichelli1, T. Brogi2, S. Marucci2, D. Pastori2, P. Pignatelli2 | 1Department of General Surgery and Surgical Specialty, Sapienza University of Roma; 2Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.306
    382
    PDF: 0
  • CO09 | Long term effectiveness and safety of direct oral anticoagulants in patients with factor V Leiden and/or prothrombin gene mutation and venous thromboembolism: a single centre, retrospective cohort study I.M. Palumbo1, E. Valeriani1,2, A. Pannunzio1, S. Marucci3, D. Menichelli1, D. Pastori3,4, P. Pignatelli3 | 1Department of General Surgery and Surgical Specialty, Sapienza University of Roma; 2Department of Infectious Disease, Azienda Ospedaliero-Universitaria Policlinico Umberto I, Roma; 3Department of Clinical Internal, Anaesthesiologic and Cardiovascular Sciences, Sapienza University of Roma; 4IRCCS Neuromed, Pozzilli, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.213
    446
    PDF: 0
  • Role of platelet autophagy in cardiovascular diseases

    Luca D'Ambrosio, Maurizio Forte, Giacomo Frati, Sebastiano Sciarretta
    26-08-2024
    https://doi.org/10.4081/btvb.2024.133
    1178
    PDF: 271
  • Talking about assisted reproductive techniques and thromboembolic risk: everything we always wanted to know

    Giovanni Tiscia, Elvira Grandone
    13-09-2022
    https://doi.org/10.4081/btvb.2022.43
    2377
    PDF: 299
  • CO25 | Thromboinflammation and ros accumulation in individuals with high lipoprotein(a) levels M. Frezza1, P.G.M. Simeone1, M. Alfonsetti1, R. Liani1, M. Cellini1, P. Del Boccio2, M.C. Cufaro3, O. Iuliani4, A. Quaglietta4, F. Cipollone1, F. Santilli1 | 1Department of Medicine and Ageing Sciences, Center for Advanced Studies and Technology “CAST”, University of Chieti; 2Department of Pharmacy, Center for Advanced Studies and Technology “CAST”, Chieti; 3Department of Innovative Technologies in Medicine and Dentistry, Center for Advanced Studies and Technology “CAST”, Chieti; 4Department of Haematolgy and Oncology, Center of Transfusion Medicine, Pescara General Hospital, Pescara. Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.231
    412
    PDF: 0
  • Well begun is half done

    Giovanni de Gaetano
    14-12-2022
    https://doi.org/10.4081/btvb.2022.61
    1695
    PDF: 218
  • CO52 | The impact of KRAS mutations on the risk of recurrent venous thromboembolism in patients with cancer-associated thrombosis and gastrointestinal neoplasms B. Cosmi1,2, S. Cavara2, M. Soldati2, L. Borgese2, M. Sartori2 | 1Angiology and Blood Coagulation Unit, Department of Medical and Surgical Sciences, University of Bologna; 2Angiology and Blood Coagulation Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.262
    374
    PDF: 0
  • Milvexian and other drugs targeting Factor XI: a new era of anticoagulation?

    Marco P. Donadini, Walter Ageno
    15-04-2022
    https://doi.org/10.4081/btvb.2022.22
    2235
    PDF: 598
  • CO08 | The utility of urine qualitative assessment for direct oral anticoagulants in routine clinical practice F. Schieppati1,2, P. Gomez-Rosas1,3, C. Ambaglio1, V. Brusegan1, Oc. Cretu1,2, E. Galimberti1, F. Zunino1, L. Barcella1, J. Harenberg4,5, A. Falanga1,2, M. Marchetti1,2 | 1Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; 2School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; 3Maastricht University Medical Center, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands; 4Ruprecht Karls University of Heidelberg, Germany; 5Germany DOASENSE GmbH, Heidelberg, Germany

    22-10-2025
    https://doi.org/10.4081/btvb.2025.212
    466
    PDF: 0
  • PO69 | Whole blood thrombin generation hypercoagulable profile in a patient with hemolytic crisis due to paroxysmal nocturnal hemoglobinuria: a case report A. Napolitano, L. Spiezia, C. Bulato, E. Campello, P. Simioni | First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.338
    430
    PDF: 0
  • Clonal hematopoiesis and inflammation: a link with thrombosis and malignancy

    Tiziano Barbui
    21-07-2022
    https://doi.org/10.4081/btvb.2022.38
    3029
    PDF: 360
  • CO17 | Clinical relevance of isolated anti-phosphatidylserine/ prothrombin antibody positivity A. Hoxha1, P. Žigon2,3, L. Katja2,3, S. Čučnik2,4, Ž. Rotar2,5, S. Gavasso1, P. Zerbinati1, G. Gobbo1, P. Simioni1 | 1University of Padua, Internal Medicine Unit, Thrombotic and Hemorrhagic Centre, Department of Medicine-DIMED, Padua, Italy; 2University Medical Centre Ljubljana, Department of Rheumatology, Ljubljana, Slovenia; 3University of Primorska, Faculty of Mathematics, Natural Sciences and Information Technologies, Koper, Slovenia; 4University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia; 5University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia

    22-10-2025
    https://doi.org/10.4081/btvb.2025.221
    390
    PDF: 0
  • Antithrombotic therapy in idiopathic infertility

    Fabio Tumminello, Silvia Cardi, Corrado Lodigiani, Maria Elisa Mancuso
    03-10-2024
    https://doi.org/10.4081/btvb.2024.126
    2610
    PDF: 555
  • What is the gender of thrombosis? A natural model of precision medicine

    Rossella Marcucci, Rosanna Abbate
    03-08-2023
    https://doi.org/10.4081/btvb.2023.87
    729
    PDF: 236
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Vol. 4 No. 3 (2025)
Persistence of functional anti-PF4 antibodies and neutrophil activation in vaccine-induced immune thrombotic thrombocytopenia
Eleonora Petito et al.
18 November 2025
Vol. 4 No. 3 (2025)
Diagnostic and management practices for inherited fibrinogen disorders: a nationwide survey of Italian Hemophilia Treatment Centers
Renato Marino et al.
2 December 2025
Vol. 4 No. 3 (2025)
Gene therapy for hemophilia B
Pier Mannuccio Mannucci
12 December 2025

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    • VTE and Cardiovascular Diseases
    • Laboratory and Predictive Factors
    • Congenital and Acquired Hemorrhagic Diseases
    • Platelet Alterations and Genetic Conditions
    • SISET 2025 - Posters
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